Alzheimer’s: The last discovery explains how it is born
Alzheimer’s is a form of generative dementia that becomes disabling with the passing of time.
It is very developed at presenile age, i.e. over 65 years even though it can manifest itself before.
The disease is named after its discoverer, the German psychiatrist Alois Alzheimer who in 1907 studied the neuropathological aspects of a woman who had died as a result of an unknown mental illness.
An autopsy examination revealed the presence of amyloid plaques considered as the Alzheimer’s effects, which are still unknown to the cause today.
The most common symptom that appears before is the inability to remember recent events.
Generally, it manifests itself with mild memory problems until it finishes with major damage to the fabrics.
Manually appear: disorientation, depression, mood changes, aphasia, behavioral problems.
Some recent studies that we will discuss later have highlighted that depression and continual mood swings are not actually caused by Alzheimer’s disease but can be considered an alarm bell that favors early diagnosis of the disease.
In general, the person suffering from Alzheimer’s tend to isolate himself from the family and social context, often asks the same questions, is unable to follow precise directions, neglects himself, nutrition and personal hygiene.
On average, after the diagnosis of the disease, life expectancy ranges from three to nine years.
Early diagnosis of Alzheimer’s is very important and is not underestimated at all. No doubt it offers the chance to deal with some symptoms of the disease, but above all to make decisions with the patient still polished.
Currently the diagnosis consists of:
- Clinical examinations, spinal fluid, blood and urine;
- Tac celebali, to verify the presence of some anomaly;
- Neuropsychological tests aimed at measuring the problem solving capacity, the ability to talk, remember, and count.
These tests are diagnosed not only to assess Alzheimer’s but also to exclude other thyroid-related or cancerous diseases that may have similar symptoms, but would exclude neurodegenerative disease and as such should be treated differently.
Alzheimer’s last discovery
An all-Italian discovery published these days on Nature Communications reveals very important novelties for Alzheimer’s, which continues to hit about half a million Italians over 60.
According to research conducted by a group of Italian researchers from the IRCCS Foundation Santa Lucia, Cnr of Rome and the Campus Bio-Medico University, the cause of Alzheimer’s disease is not in the hippocampus, that is, in the structures that regulate memory but the person responsible for the disease would be due to the lack of dopamine production due to the death of cellular gaps.
In practice, scholars have so far focused on the brain area that affects the mechanism of memory.
In fact, other areas of the brain also contribute to pathology, such as the somatic tegmental area where dopamine is produced.
Dopamine is closely related to mood disorders and therefore motivation and gratification.
Therefore the depression that was thought to be a consequence of Alzheimer’s should be considered an alarm bell of the disease.
Research therefore highlights that depression and memory loss are two faces of the same medal that should not be underestimated.